| Date | Title | Author | Journal | |
|---|---|---|---|---|
| 7/19/2018 | Purification of mRNA encoding chimeric antigen receptor is critical for generation of robust T cell response | Jessica B Foster, Namrata Choudhari,Jessica Perazzelli, Julie Storm,Ted J Hofmann, Payal Jain, Phillip B Storm, Norbert Pardi, Drew Weissman,Angela J Waanders, Stephan A Grupp, Katalin Karikó, Adam C Resnick, PhD, David M Barrett | Human gene therapy | Details |
| 7/19/2018 | Purification of mRNA encoding chimeric antigen receptor is critical for generation of robust T cell response | Foster, J. B., Choudhari, N., Perezzelli, J., Storm, J., Hofmann, T. J., Jain, P., ... & Grupp, S. A. | Human gene therapy | Details |
| 3/16/2018 | Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation | Jain, Payal, Lea F. Surrey, Joshua Straka, Minjie Luo, Fumin Lin, Brian Harding, Adam C. Resnick, Phillip B. Storm, Anna Maria Buccoliero, Mariarita Santi, Marilyn M. Li, and Angela J. Waanders | Acta Neuropathologica | Details |
| 3/5/2018 | The landscape of genomic alterations across childhood cancers | Gröbner, Susanne N., Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vasilisa A. Rudneva, Pascal D. Johann, Gnana Prakash Balasubramanian, Maia Segura-Wang, Sebastian Brabetz, Sebastian Bender, Barbara Hutter, Dominik Sturm, Elke Pfaff, Daniel Hübschmann, Gideon Zipprich, Michael Heinold, Jürgen Eils, Christian Lawerenz, Serap Erkek, Sander Lambo, Sebastian Waszak, Claudia Blattmann, Arndt Borkhardt, Michaela Kuhlen, Angelika Eggert, Simone Fulda, Manfred Gessler, Jenny Wegert, Roland Kappler, Daniel Baumhoer, Stefan Burdach, Renate Kirschner-Schwabe, Udo Kontny, Andreas E. Kulozik, Dietmar Lohmann, Simone Hettmer, Cornelia Eckert, Stefan Bielack, Michaela Nathrath, Charlotte Niemeyer, Günther H. Richter, Johannes Schulte, Reiner Siebert, Frank Westermann, Jan J. Molenaar, Gilles Vassal, Hendrik Witt, Icgc PedBrain-Seq Project, Icgc Mmml- Seq Project, Birgit Burkhardt, Christian P. Kratz, Olaf Witt, Cornelis M. van Tilburg, Christof M. Kramm, Gudrun Fleischhack, Uta Dirksen, Stefan Rutkowski, Michael Frühwald, Katja von Hoff, Stephan Wolf, Thomas Klingebiel, Ewa Koscielniak, Pablo Landgraf, Jan Koster, Adam C. Resnick, Jinghui Zhang, Yanling Liu, Xin Zhou, Angela J. Waanders, Danny A. Zwijnenburg, Pichai Raman, Benedikt Brors, Ursula D. Weber, Paul A. Northcott, Kristian W. Pajtler, Marcel Kool, Rosario M. Piro, Jan O. Korbel, Matthias Schlesner, Roland Eils, David T. W. Jones, Peter Lichter, Lukas Chavez, Marc Zapatka, and Stefan M. Pfister | Nature | Details |
| 2/25/2018 | Outcomes of Pediatric Craniopharyngioma Resections after Open versus Expanded Endonasal Surgical Approach | Douglas, Jennifer E., Bobby A. Tajudeen, Edward C. Kuan, Marvin Bergsneider, Marilene B. Wang, John Y. K. Lee, James N. Palmer, Nithin D. Adappa, and Phillip B. Storm | J Neurol Surg B | Details |
| 2/15/2018 | The effect and evolution of patient selection on outcomes in endoscopic third ventriculostomy for hydrocephalus: A large-scale review of the literature | Madsen, Peter J, Arka N Mallela, Eric D Hudgins, Phillip B Storm, Gregory G Heuer, and Sherman C Stein | Journal of the Neurological Sciences | Details |
| 2/8/2018 | Cerebrospinal Fluid Leak Repaired with Nasoseptal Flap in a 2-Week-Old Neonate | Workman, Alan D., Ivy W. Maina, Vasiliki Triantafillou, James N. Palmer, Nithin D. Adappa, Phillip B. Storm, and Jordan T. Glicksman | J Neurol Surg B | Details |
| 2/2/2018 | Posttreatment Rhinosinusitis following Endoscopic Resection of Pediatric Craniopharyngioma | Tong, Charles C., Edward C. Kuan, Seerat K. Poonia, Michael A. Kohanski, Justina L. Lambert, Phillip B. Storm, James N. Palmer, and Nithin D. Adappa | J Neurol Surg B | Details |
| 1/22/2018 | Pediatric low-grade gliomas: next biologically driven steps | Jones, D. T. W., M. W. Kieran, E. Bouffet, S. Alexandrescu, P. Bandopadhayay, M. Bornhorst, D. Ellison, J. Fangusaro, M. J. Fisher, N. Foreman, M. Fouladi, D. Hargrave, C. Hawkins, N. Jabado, M. Massimino, S. Mueller, G. Perilongo, A. Y. N. Schouten van Meeteren, U. Tabori, K. Warren, A. J. Waanders, D. Walker, W. Weiss, O. Witt, K. Wright, Y. Zhu, D. C. Bowers, S. M. Pfister, and R. J. Packer | Neuro Oncol | Details |
| 1/5/2018 | Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects | Guha, Manti, Satish Srinivasan, Pichai Raman, Yuefu Jiang, Brett A. Kaufman, Deanne Taylor, Dawei Dong, Rumela Chakrabarti, Martin Picard, Russ P. Carstens, Yuko Kijima, Mike Feldman, and Narayan G. Avadhani | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | Details |
| 1/1/2018 | Oculoplastic Considerations in Pediatric Craniofacial Surgery | Naran, Sanjay, Michael F. Spadola, Phillip B. Storm, and Scott P. Bartlett | Pediatric Oculoplastic Surgery | Details |
| 11/6/2017 | PDTM-40. PEDIATRIC LOW-GRADE GLIOMAS WITH CRAF GENE FUSIONS ARE THERAPEUTICALLY DISTINCT FROM BRAF-FUSIONS BASED ON DIMERIZATION MEDIATED BY N-TERMINAL FUSION PARTNER | Jain, Payal, Tamara Fierst, Harry Han, Tiffany Smith, Phillip B. Storm, Angela J. Waanders, and Adam C. Resnick | Neuro-Oncology | Details |
| 11/6/2017 | EXTH-58. EFFECTS OF TORC1/2 INHIBITOR MLN0128 ALONE AND IN COMBINATION WITH MEK INHIBITION IN BRAF MUTATED GLIOMA MODELS IN VITRO AND IN VIVO | Liu, Kevin X., Sabine Mueller, Rogier Dik, Xiaodong Yang, Steven DuBois, Angela J. Waanders, Adam C. Resnick, William A. Weiss, and Daphne Haas-Kogan | Neuro-Oncology | Details |
| 11/1/2017 | Developing Cancer Informatics Applications and Tools Using the NCI Genomic Data Commons API | Wilson, Shane, Michael Fitzsimons, Martin Ferguson, Allison Heath, Mark Jensen, Josh Miller, Mark W. Murphy, James Porter, Himanso Sahni, Louis Staudt, Yajing Tang, Zhining Wang, Christine Yu, Junjun Zhang, Vincent Ferretti, and Robert L. Grossman | Cancer Research | Details |
| 10/18/2017 | Comprehensive Analysis of Hypermutation in Human Cancer | Campbell, Brittany B., Nicholas Light, David Fabrizio, Matthew Zatzman, Fabio Fuligni, Richard de Borja, Scott Davidson, Melissa Edwards, Julia A. Elvin, Karl P. Hodel, Walter J. Zahurancik, Zucai Suo, Tatiana Lipman, Katharina Wimmer, Christian P. Kratz, Daniel C. Bowers, Theodore W. Laetsch, Gavin P. Dunn, Tanner M. Johanns, Matthew R. Grimmer, Ivan V. Smirnov, Valérie Larouche, David Samuel, Annika Bronsema, Michael Osborn, Duncan Stearns, Pichai Raman, Kristina A. Cole, Phillip B. Storm, Michal Yalon, Enrico Opocher, Gary Mason, Gregory A. Thomas, Magnus Sabel, Ben George, David S. Ziegler, Scott Lindhorst, Vanan Magimairajan Issai, Shlomi Constantini, Helen Toledano, Ronit Elhasid, Roula Farah, Rina Dvir, Peter Dirks, Annie Huang, Melissa A. Galati, Jiil Chung, Vijay Ramaswamy, Meredith S. Irwin, Melyssa Aronson, Carol Durno, Michael D. Taylor, Gideon Rechavi, John M. Maris, Eric Bouffet, Cynthia Hawkins, Joseph F. Costello, M. Stephen Meyn, Zachary F. Pursell, David Malkin, Uri Tabori, and Adam Shlien | Cell | Details |
| 10/12/2017 | Novel findings with reassessment of exome data: implications for validation testing and interpretation of genomic data | Gibson, Kristin McDonald, Addie Nesbitt, Kajia Cao, Zhenming Yu, Elizabeth Denenberg, Elizabeth DeChene, Qiaoning Guan, Elizabeth Bhoj, Xiangdong Zhou, Bo Zhang, Chao Wu, Holly Dubbs, Alisha Wilkens, Livija Medne, Emma Bedoukian, Peter S. White, Jeffrey Pennington, Minjie Lou, Laura Conlin, Dimitri Monos, Mahdi Sarmady, Eric Marsh, Elaine Zackai, Nancy Spinner, Ian Krantz, Matt Deardorff, and Avni Santani | Genetics in Medicine | Details |
| 10/9/2017 | Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma | Mackay, Alan, Anna Burford, Diana Carvalho, Elisa Izquierdo, Janat Fazal-Salom, Kathryn R. Taylor, Lynn Bjerke, Matthew Clarke, Mara Vinci, Meera Nandhabalan, Sara Temelso, Sergey Popov, Valeria Molinari, Pichai Raman, Angela J. Waanders, Harry J. Han, Saumya Gupta, Lynley Marshall, Stergios Zacharoulis, Sucheta Vaidya, Henry C. Mandeville, Leslie R. Bridges, Andrew J. Martin, Safa Al-Sarraj, Christopher Chandler, Ho-Keung Ng, Xingang Li, Kun Mu, Saoussen Trabelsi, Dorra H’mida-Ben Brahim, Alexei N. Kisljakov, Dmitry M. Konovalov, Andrew S. Moore, Angel Montero Carcaboso, Mariona Sunol, Carmen de Torres, Ofelia Cruz, Jaume Mora, Ludmila I. Shats, João N. Stavale, Lucas T. Bidinotto, Rui M. Reis, Natacha Entz-Werle, Michael Farrell, Jane Cryan, Darach Crimmins, John Caird, Jane Pears, Michelle Monje, Marie-Anne Debily, David Castel, Jacques Grill, Cynthia Hawkins, Hamid Nikbakht, Nada Jabado, Suzanne J. Baker, Stefan M. Pfister, David T. W. Jones, Maryam Fouladi, André O. von Bueren, Michael Baudis, Adam Resnick, and Chris Jones | Cancer Cell | Details |
| 9/22/2017 | GPC2 MAY BE AN IMMUNOTHERAPEUTIC TARGET IN HIGH-RISK NEUROBLASTOMA | Bosse, KR, P Raman, Z Zhu, M Lane, D Martinez, and S Heitzeneder | AMER ASSOC CANCER RESEARCH | Details |
| 9/15/2017 | Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways | Jain, P., A. Silva, H. J. Han, S. S. Lang, Y. Zhu, K. Boucher, T. E. Smith, A. Vakil, P. Diviney, N. Choudhari, P. Raman, C. M. Busch, T. Delaney, X. Yang, A. K. Olow, S. Mueller, D. Haas-Kogan, E. Fox, P. B. Storm, A. C. Resnick, and A. J. Waanders | Oncotarget | Details |
| 9/11/2017 | Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma | Bosse, Kristopher R., Pichai Raman, Zhongyu Zhu, Maria Lane, Daniel Martinez, Sabine Heitzeneder, Komal S. Rathi, Nathan M. Kendsersky, Michael Randall, Laura Donovan, Sorana Morrissy, Robyn T. Sussman, Doncho V. Zhelev, Yang Feng, Yanping Wang, Jennifer Hwang, Gonzalo Lopez, Jo Lynne Harenza, Jun S. Wei, Bruce Pawel, Tricia Bhatti, Mariarita Santi, Arupa Ganguly, Javed Khan, Marco A. Marra, Michael D. Taylor, Dimiter S. Dimitrov, Crystal L. Mackall, and John M. Maris | Cancer Cell | Details |
| 8/14/2017 | CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles | Jain, P., T. M. Fierst, H. J. Han, T. E. Smith, A. Vakil, P. B. Storm, A. C. Resnick, and A. J. Waanders | Oncogene | Details |
| 8/2/2017 | Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases | Han, Harry J., Payal Jain, and Adam C. Resnick | Bone | Details |
| 7/1/2017 | Abstract 4887: Comprehensive molecular analysis of pediatric thalamic tumors | Moser, Heloisa H., Susanne Yoon, Madhuri Kambhampati, Sridevi Yadavilli, Angela J. Waanders, Adam Resnick, Roger J. Packer, and Javad Nazarian | Cancer Research | Details |
| 7/1/2017 | Abstract LB-008: The Pediatric Brain Tumor Atlas: building an integrated, multi-platform data-rich ecosystem for collaborative discovery in the cloud | Resnick, Adam C., Phillip B. Storm, Angela J. Waanders, Jena V. Lilly, Rishi R. Lulla, Sabine Mueller, Michael Prados, Leonard S. Sender, Allison Heath, Alex S. Felmeister, Anthony Cros, Yuankun Zhu, and Pichai Raman | Cancer Research | Details |
| 7/1/2017 | Abstract 2593: Accelerating pediatric brain tumor research through team science solutions | Christini, Amanda, Angela J. Waanders, Joost B. Wagenaar, Alex S. Felmeister, Mariarita Santi, Nitin R. Wadhwani, Jennifer L. Mason, Mateusz P. Koptyra, Jena V. Lilly, Jeffrey W. Pennington, Rishi R. Lulla, and Adam C. Resnick | Cancer Research | Details |
| 7/1/2017 | Abstract 5614: Novel mRNA purification method with RNaseIII improves efficacy of RNA chimeric antigen receptor T cells | Foster, Jessica, Namrata Choudhari, Adam Resnick, and David Barrett | Cancer Research | Details |
| 7/1/2017 | Abstract 2607: The cBioPortal for Cancer Genomics: an open source platform for accessing and interpreting complex cancer genomics data in the era of precision medicine | Gao, Jianjiong, Ersin Ciftci, Pichai Raman, Pieter Lukasse, Istemi Bahceci, Adam Abeshouse, Hsiao-Wei Chen, Ino de Bruijn, Benjamin Gross, Zachary Heins, Ritika Kundra, Aaron Lisman, Angelica Ochoa, Robert Sheridan, Onur Sumer, Yichao Sun, Jiaojiao Wang, Manda Wilson, Hongxin Zhang, James Xu, Andy Dufilie, Priti Kumari, James Lindsay, Anthony Cros, Karthik Kalletla, Fedde Schaeffer, Sander Tan, Sjoerd van Hagen, Jorge Reis-Filho, Kees van Bochove, Ugur Dogrusoz, Trevor Pugh, Adam Resnick, Chris Sander, Ethan Cerami, and Nikolaus Schultz | Cancer Research | Details |
| 7/1/2017 | Abstract 3000: Defining the subclonal landscape of high-risk neuroblastoma | Harenza, Jo Lynne, Maura A. Diamond, Derek A. Oldridge, Olivia Padovan-Merher, Pichai Raman, Yael P. Mosse, and John M. Maris | Cancer Research | Details |
| 6/30/2017 | The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma | Capasso, Mario, Lee D. McDaniel, Flora Cimmino, Andrea Cirino, Daniela Formicola, Mike R. Russell, Pichai Raman, Kristina A. Cole, and Sharon J. Diskin | Journal of Cellular and Molecular Medicine | Details |
| 6/3/2017 | Data Commons to Support Pediatric Cancer Research | Volchenboum, SL, SM Cox, A Heath, A Resnick, SL Cohn, and R Grossman | American Society of Clinical Oncology | Details |
| 5/31/2017 | GERM-01. GENETIC AND EPIGENETIC LANDSCAPE OF CENTRAL NERVOUS SYSTEM GERM CELL TUMORS | Ichimura, Koichi, Yoshiko Nakano, Kai Yamasaki, Mai Kitahara, Kaishi Satomi, Hirokazu Takami, Shintaro Fukushima, Masao Matsutani, and Ryo Nishikawa | Neuro-Oncology | Details |
| 5/26/2017 | Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression | Kim, E., Y. Cheng, E. Bolton-Gillespie, X. Cai, C. Ma, A. Tarangelo, L. Le, M. Jambhekar, P. Raman, K. E. Hayer, G. Wertheim, N. A. Speck, W. Tong, and P. Viatour | J Exp Med | Details |
| 2/20/2017 | Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing | Lurier, Emily B., Donald Dalton, Will Dampier, Pichai Raman, Sina Nassiri, Nicole M. Ferraro, Ramakrishan Rajagopalan, Mahdi Sarmady, and Kara L. Spiller | Immunobiology | Details |
| 8/18/2016 | The Biorepository Portal Toolkit: An Honest Brokered, Modular Service Oriented Software Tool Set for Biospecimen-driven Translational Research | Alex S. Felmeister, Aaron J. Masino, Tyler J. Rivera, Adam C. Resnick and Jeffrey W. Pennington, The Children's Hospital of Philadelphia, Department of Biomedical & Health Informatics | BMC Genomics | Details |
| 2/1/2016 | MYB-QKI Rearrangements in Angiocentric Glioma Drive Tumorigenicity Through a Tripartite Mechanism | Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC | PubMed | Details |
| 11/12/2015 | Scalable Biobanking: A Modular Electronic Honest Broker and Biorepository for Integrated Clinical, Specimen and Genomic Research | Felmeister, Alex S.; Rivera, Tyler J.; Masino, Aaron J.; Resnick, Adam C.; Pennington, Jeffrey W., Children's Hospital of Philadelphia, Department of Biomedical and Health Informatics | Bioinformatics and Biomedicine (BIBM) | Details |
| 2/14/2014 | Exome Sequencing Identifies BRAF Mutations in Papillary Craniopharyngiomas | Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, Martinez-Lage M, Santi M, Storm PB, Lee JY, Palmer JN, Adappa ND, Scott RM, Dunn IF, Laws ER Jr, Stewart C, Ligon KL, Hoang MP, Van Hummelen P, Hahn WC, Louis DN, Resnick AC, Kieran MW, Getz G, Santagata S. | PubMed | Details |
| 1/28/2011 | The Genetic Landscape of the Childhood Cancer Medulloblastoma | Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. | PubMed | Details |
| 7/12/2010 | Activating Mutations in BRAF Characterize a Spectrum of Pediatric Low-grade Gliomas | Dougherty MJ, Santi M, Brose MS, Ma C, Resnick AC, Sievert AJ, Storm PB, Biegel JA | PubMed | Details |
