CHOP CBTCC investigatorsThe CBTTC’s goal is to freely share biospecimens, data, and ideas. Researchers are invited to view the available specimens and data on the informatics platform, the CBTTC Data and Specimen Inventory Portal.

Joining CBTTC

To be considered for CBTTC membership, an institution shall meet the following criteria:

  • Treats patients with nervous system tumors and has a large annual accrual of patients who undergo surgical resection of their brain tumors
  • Has a scientific infrastructure to support participation in the CBTTC
  • Is willing to contribute childhood brain tumors open biopsy samples from at least 75% of all childhood brain tumor specimens submitted to their pathology department
  • Has or will obtain a Federal Wide Assurance

Contact us for membership inquiries.

CBTTC Data Submission

BRP: The Biorepository portal is the informatics platform for CBTTC data and tissue submission. The BRP uses REDCap as the data collection tool. In the BRP clinical data is collected as shown below for each subject. You must be an approved CBTTC consortium member to enter data into the BRP. To request an account and training please select register for account on the BRP website.


  • Gender
  • Subject Age at Initial Diagnosis
  • Ethnicity
  • Race

Diagnosis and Progression

  • Metastases at Submission
  • Operations Center Pathology Review
  • Recurrent
  • Tumor Primary Location In CNS
  • Initial Pathology Diagnosis

Molecular Testing

  • Tumor Or Molecular Tests Done
  • History
  • Cancer Predisposition
  • Family History
  • Other Medical Condition

Follow Up Data

  • Additional Tumor Molecular Test at Update
  • Tumor Site of Progression
  • Recurrence Pathology Diagnosis at Update (Referring Institution)
  • Update Type
  • Subject Clinical Status at Update
  • Update Tumor Primary Location
    Relapse Number
  • Metastatic Site

CBTTC Data and Specimen Inventory

The CBTTC Data and Specimen Inventory Portal Platform provides access to the de-identified pediatric brain tumor specimens and annotated data that is currently available for research. Please contact us to apply for use.

The Specimen Inventory includes:

  • Fresh Frozen Tissue
  • Snap Frozen Tissue
  • Blood from the subject
  • Cerebral Spinal Fluid
  • Tissue slides and slide images

WIKI: The CHOP CBTTC Wiki share is a place for collaborators and partners to share information discuss topics and work towards achieving the objectives, mission, and vision of the CBTTC. You will find the following information in the Wiki share:

  • Standard Operating procedures
  • Regulatory Documents
  • Current Projects
  • Contact information

Please contact us with any questions.

Contact CBTTC